MEDACLOX

Medaclox Capsule

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

MEDACLOX 500 mg

Generic Name: Cloxacillin 500mg capsule and 125mg/5ml suspension
Class: Antibacterial

” The TRIED and TESTED Antibacterial for Staphylococcal Infections”

INDICATION:

Used primarily for the treatment of infections due to staphylococci which are resistant to benzylpenicillin. It is also used for mixed streptococcal and staphylococcal infections when the staphylococcal are penicillin-resistant. Cloxacillin is sometimes given with ampicillin in infections due to beta-lactamase-producing Gram-negative organisms since it may inhibit the destruction of ampicillin.

Used in skin and soft tissue infections like furuncles, carbuncles, impetigo, folliculitis. Also in wounds and burns, ENT infections.

PHARMACOKINETICS:

  • Bio-availability after oral administration: 37 to 60%
  • Acid stable (pH 1.9)
  • If given with food, both the rate and absorption is decreased
  • Peak plasma levels: Within 45 minutes to 1 hour
  • Half life: 56 minutes
  • 90-95% bound to plasma protein
  • Diffuses across placenta; excreted in breast milk
  • Excretion: Urine (35%), Bile (10%), Feces (+/-)