Medaclox Capsule






















Generic Name: Cloxacillin 500mg capsule and 125mg/5ml suspension
Class: Antibacterial

” The TRIED and TESTED Antibacterial for Staphylococcal Infections”


Used primarily for the treatment of infections due to staphylococci which are resistant to benzylpenicillin. It is also used for mixed streptococcal and staphylococcal infections when the staphylococcal are penicillin-resistant. Cloxacillin is sometimes given with ampicillin in infections due to beta-lactamase-producing Gram-negative organisms since it may inhibit the destruction of ampicillin.

Used in skin and soft tissue infections like furuncles, carbuncles, impetigo, folliculitis. Also in wounds and burns, ENT infections.


  • Bio-availability after oral administration: 37 to 60%
  • Acid stable (pH 1.9)
  • If given with food, both the rate and absorption is decreased
  • Peak plasma levels: Within 45 minutes to 1 hour
  • Half life: 56 minutes
  • 90-95% bound to plasma protein
  • Diffuses across placenta; excreted in breast milk
  • Excretion: Urine (35%), Bile (10%), Feces (+/-)